van Petegem, Filip: search on Z-Library

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1

Calcium Channelopathies: Structural Insights into Disorders of the Muscle Excitation–Contraction Complex

Pancaroglu, Raika, Van Petegem, Filip

Journal:

Annual Review of Genetics

Year:

2018

Language:

english

File:

PDF, 4.13 MB

english, 2018

2

Multiple C-terminal tail Ca2+/CaMs regulate CaV1.2 function but do not mediate channel dimerization

Kim, Eun Young, Rumpf, Christine H, Van Petegem, Filip, Arant, Ryan J, Findeisen, Felix, Cooley, Elizabeth S, Isacoff, Ehud Y, Minor, Daniel L

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 2.21 MB

english, 2010

3

A multi-dimensional analysis of genotypeâphenotype discordance in malignant hyperthermia susceptibility

Ibarra Moreno, Carlos A., Kraeva, Natalia, Zvaritch, Elena, Figueroa, Lourdes, Rios, Eduardo, Biesecker, Leslie, Van Petegem, Filip, Hopkins, Philip M., Riazi, Sheila

Journal:

British Journal of Anaesthesia

Year:

2020

File:

PDF, 768 KB

2020

4

Ryanodine Receptors: Allosteric Ion Channel Giants

Van Petegem, Filip

Journal:

Journal of Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

5

Crystal structure of Sulfolobus acidocaldarius aspartate carbamoyltransferase in complex with its allosteric activator CTP

Dirk De Vos, Ying Xu, Tony Aerts, Filip Van Petegem, Jozef J. Van Beeumen

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 852 KB

english, 2008

6

Binary Architecture of the Nav1.2-β2 Signaling Complex

Gilchrist, John M., Das, Samir, Van Petegem, Filip, Bosmans, Frank

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 45 KB

english, 2016

7

Ca 2+ dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

Brohus, Malene, Søndergaard, Mads Toft, Chen, S.R. Wayne, Van Petegem, Filip, Overgaard, Michael Toft

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 9.30 MB

english, 2018

8

Slaying a giant: Structures of calmodulin and protein kinase a bound to the cardiac ryanodine receptor

Van Petegem, Filip

Journal:

Year:

2019

Language:

english

File:

PDF, 749 KB

english, 2019

9

Conformational Dynamics inside Amino-Terminal Disease Hotspot of Ryanodine Receptor

Zhong, Xiaowei, Liu, Ying, Zhu, Li, Meng, Xing, Wang, Ruiwu, Van Petegem, Filip, Wagenknecht, Terence, Chen, S.R. Wayne, Liu, Zheng

Journal:

Year:

2013

Language:

english

File:

PDF, 2.47 MB

english, 2013

10

β Strand Switching: A Novel Structural Rescue Mechanism in a Δexon3 Cardiac Ryanodine Receptor Mutant

Lobo, Paolo A., Kimlicka, Lynn, Tung, Ching-Chieh, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

11

The structural biology of ryanodine receptors

Lynn Kimlicka, Filip Van Petegem

Journal:

SCIENCE CHINA Life Sciences

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

12

Evolution, Structure and Function of Ryanodine Receptor Domains

Yuchi, Zhiguang, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

13

Structural Insights into Ryanodine Receptor-FKBP12 Interactions in Wild-Type and Mutated States

Yuchi, Zhiguang, Wong King Yuen, Siobhan M., Lau, Kelvin, Underhill, Ainsley, Cornea, Razvan, Fessenden, James, Petegem, Filip Van

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 48 KB

english, 2016

14

Identification of Major FKBP12 Binding Determinants in RyR1

Cornea, Razvan L., Van Petegem, Filip, Fessenden, James D.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

15

The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations

Gardill, Bernd R., Rivera-Acevedo, Ricardo E., Tung, Ching-Chieh, Okon, Mark, McIntosh, Lawrence P., Van Petegem, Filip

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 6.75 MB

english, 2018

16

Crystal structures of Ca 2+ –calmodulin bound to Na V C-terminal regions suggest role for EF-hand domain in binding and inactivation

Gardill, Bernd R., Rivera-Acevedo, Ricardo E., Tung, Ching-Chieh, Van Petegem, Filip

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

Language:

english

File:

PDF, 2.30 MB

english, 2019

17

A Mathematical Model for Ligand Potency in the HCN2 Channel

Ng, Leo, Zhuang, Meiying, Van Petegem, Filip, Li, Yue-Xian, Accili, Eric

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 45 KB

2020

18

Crystal Structure of the Navβ4 Extracellular Domain

Das, Samir, Gilchrist, John, Bosmans, Frank, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

19

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca 2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

Søndergaard, Mads Toft, Liu, Yingjie, Larsen, Kamilla Taunsig, Nani, Alma, Tian, Xixi, Holt, Christian, Wang, Ruiwu, Wimmer, Reinhard, Van Petegem, Filip, Fill, Michael, Chen, S. R. Wayne, Overgaard,

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 3.07 MB

english, 2017

20

The Cardiac Channel Na V 1.5 Inactivation is Modulated by its C-Terminal EF-hand Domain

Gardill, Bernd R., Tung, Ching-Chieh, Rivera-Acevedo, Ricardo E., Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 44 KB

english, 2017

21

Arrhythmogenic Calmodulin Mutations Can Disrupt the Globular Structure and Uncouple Ca2+ Binding Cooperativity

Wang, Kaiqian, Brohus, Malene, Holt, Christian, Overgaard, Michael T., Wimmer, Reinhard, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 49 KB

2020

22

Structure of a complex between a voltage-gated calcium channel β-subunit and an α-subunit domain

Van Petegem, Filip, Clark, Kimberly A., Chatelain, Franck C., Minor, Daniel L.

Journal:

Year:

2004

Language:

english

File:

PDF, 394 KB

english, 2004

23

The H29D Mutation Does Not Enhance Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor

Xiao, Zhichao, Guo, Wenting, Yuen, Siobhan M. Wong King, Wang, Ruiwu, Zhang, Lin, Van Petegem, Filip, Chen, S. R. Wayne, Beard, Nicole

Journal:

Year:

2015

Language:

english

File:

PDF, 3.91 MB

english, 2015

24

Lobe-Specific Calmodulin Binding to Different Ryanodine Receptor Isoforms

Lau, Kelvin, Chan, Mandy M. Y., Van Petegem, Filip

Journal:

Year:

2014

Language:

english

File:

PDF, 2.43 MB

english, 2014

25

On the Integration of Need-related Autobiographical Memories among Late Adolescents and Late Adults: The Role of Depressive Symptoms and Self-congruence

van der Kaap-Deeder, Jolene, Vansteenkiste, Maarten, Van Petegem, Stijn, Raes, Filip, Soenens, Bart

Journal:

European Journal of Personality

Year:

2016

Language:

english

File:

PDF, 720 KB

english, 2016

26

STAC proteins associate to the IQ domain of Ca V 1.2 and inhibit calcium-dependent inactivation

Campiglio, Marta, Costé de Bagneaux, Pierre, Ortner, Nadine J., Tuluc, Petronel, Van Petegem, Filip, Flucher, Bernhard E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

27

Characterization of Arrhythmia Mutations in Calmodulin and their Interactions with the Voltage-Gated Calcium Channel

Wang, Kaiqian, Holt, Christian, Lu, Jocelyn, Brohus, Malene, Larsen, Kamilla T., Overgaard, Michael T., Wimmer, Reinhard, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 51 KB

english, 2019

28

Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface

Kimlicka, Lynn, Lau, Kelvin, Tung, Ching-Chieh, Van Petegem, Filip

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 2.91 MB

english, 2013

29

The N-Terminal Disease Hot Spot of Ryanodine Receptors Forms a Cytoplasmic Vestibule

Van Petegem, Filip, Tung, Ching-Chieh, Lobo, Paolo A., Kimlicka, Lynn

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 35 KB

english, 2011

30

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain

Lau, Kelvin, Van Petegem, Filip

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 2.82 MB

english, 2014

31

Structural Comparisons of Immunoglobulin Folds of Human Navβ Subunits

Das, Samir, Gilchrist, John, Bosmans, Frank, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 62 KB

english, 2016

32

Multiple C-terminal tail Ca2+/CaMs regulate CaV1.2 function but do not mediate channel dimerization

Kim, Eun Young, Rumpf, Christine H, Van Petegem, Filip, Arant, Ryan J, Findeisen, Felix, Cooley, Elizabeth S, Isacoff, Ehud Y, Minor, Daniel L

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

33

Understanding Nicotinamide Dinucleotide Cofactor and Substrate Specificity in Class I Flavoprotein Disulfide Oxidoreductases: Crystallographic Analysis of a Glutathione Amide Reductase

Filip Van Petegem, Dirk De Vos, Savvas Savvides, Bjorn Vergauwen, Jozef Van Beeumen

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.06 MB

english, 2007

34

Studies in the Binding of Calmodulin to Skeletal and Cardiac Ryanodine Receptors

Lau, Kelvin, Chan, Mandy M.Y., Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 35 KB

english, 2011

35

Paramagnetic Ligand Tagging to Identify Protein Binding Sites

Brath, Ulrika, Swamy, Shashikala I., Veiga, Alberte X., Tung, Ching-Chieh, Van Petegem, Filip, Erdelyi, Mate

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 594 KB

english, 2015

36

Characterization of Zebrafish Cardiac and Slow Skeletal Troponin C Paralogs by MD Simulation and ITC

Stevens, Charles M., Rayani, Kaveh, Genge, Christine E., Singh, Gurpreet, Liang, Bo, Roller, Janine M., Li, Cindy, Li, Alison Yueh, Tieleman, D. Peter, van Petegem, Filip, Tibbits, Glen F.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 2.86 MB

english, 2016

37

Subtle changes in the combining site of the Chlamydiaceae-specific mAb S25-23 increase antibody-carbohydrate binding affinity by an order of magnitude

Haji-Ghassemi, Omid, Müller-Loennies, Sven, Brooks, Cory L., MacKenzie, Colin Roger, Caveney, Nathanael, Van Petegem, Filip, Brade, Lore, Kosma, Paul, Brade, Helmut, Evans, Stephen V.

Journal:

Year:

2018

Language:

english

File:

PDF, 5.13 MB

english, 2018

38

Crystal Structures of Calcium-Loaded Calmodulin in Complex with C-Terminal Domains of Voltage-Gated Sodium Channels

Van Petegem, Filip, Tung, Ching-Chieh, Gardill, Bernd, Rivera-Acevedo, Ricardo E.

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 45 KB

2020

39

Seeing the Forest through the Trees: towards a Unified View on Physiological Calcium Regulation of Voltage-Gated Sodium Channels

Van Petegem, Filip, Lobo, Paolo A., Ahern, Christopher A.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 830 KB

english, 2012

40

Crystallographic Insights into the Cardiac Ryanodine Receptor N-terminal Domain and its Disease Mutants

Lobo, Paolo A., Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

41

Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic α-Helix That Transitions to a β-Strand in a Mutant Linked with a Heritable Cardiomyopathy

Amador, Fernando J., Kimlicka, Lynn, Stathopulos, Peter B., Gasmi-Seabrook, Geneviève M.C., MacLennan, David H., Van Petegem, Filip, Ikura, Mitsuhiko

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

42

Molecular interactions between sex hormone-binding globulin and non-steroidal ligands that enhance androgen action

Round, Phillip, Das, Samir, Wu, Tsung-Sheng, Wähälä, Kristiina, Van Petegem, Filip, Hammond, Geoffrey L.

Journal:

Journal of Biological Chemistry

Year:

2019

File:

PDF, 4.83 MB

2019

43

Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling

Rufenach, Britany, Christy, Darren, Flucher, Bernhard E., Bui, Jennifer M., Gsponer, JÃ¶rg, Campiglio, Marta, Van Petegem, Filip

Journal:

Year:

2020

File:

PDF, 3.05 MB

2020

44

Folding properties of the hepatitis B core as a carrier protein for vaccination research

Michiel Etienne Janssens, Dirk Geysen, Katleen Broos, Ine De Goeyse, Johan Robbens, Filip Van Petegem, Jean-Pierre Timmermans, Yves Guisez

Journal:

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010

45

Catecholaminergic polymorphic ventricular tachycardia

Roston, Thomas M., Van Petegem, Filip, Sanatani, Shubhayan

Journal:

Current Opinion in Cardiology

Year:

2017

Language:

english

File:

PDF, 541 KB

english, 2017

46

The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule

Tung, Ching-Chieh, Lobo, Paolo A., Kimlicka, Lynn, Van Petegem, Filip

Journal:

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

47

Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL+ chronic myeloid leukemia cells to tyrosine kinase inhibitors

Xiaohu Liu, Min Chen, Paolo Lobo, Jianghong An, S.W. Grace Cheng, Annie Moradian, Gregg B. Morin, Filip Van Petegem, Xiaoyan Jiang

Journal:

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

48

Structural Insight into the Phosphorylation Domain in Ryanodine Receptors

Yuchi, Zhiguang, Lau, Kelvin, Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 38 KB

english, 2013

49

A Thermodynamic Analysis of Disease-Causing Mutations in the Nav1.5 C-Terminus

Tung, Ching-Chieh, Rivera-Acevedo, Ricardo E., Gardill, Bernd R., Van Petegem, Filip

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

50

Ryanodine receptors under the magnifying lens: Insights and limitations of cryo-electron microscopy and X-ray crystallography studies

Yuchi, Zhiguang, Van Petegem, Filip

Journal:

Year:

2016

Language:

english

File:

PDF, 8.62 MB

english, 2016

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